Adenosine deaminase 2 (ADA2) plays a critical role in immune regulation, particularly in monocyte differentiation and ...

By shutting this “off switch,” immune cells called macrophages regain their ability to soak up cholesterol, potentially ...

Researchers at UT Arlington have discovered a key enzyme, IDO1, that when blocked, helps immune cells regain their ability to ...

Scientists at The University of Texas at Arlington have identified a new enzyme that can be "turned off" to help the body ...

Scientists at The University of Texas at Arlington have identified a new enzyme that can be "turned off" to help the body ...

Many people with IBD, an umbrella term that includes ulcerative colitis and Crohn's disease, have a reduced quality of life, ...

How do drug metabolizing enzymes such as CYP2D6 influence pharmacokinetics and drug efficiency of tamoxifen and aromatase inhibitors in adjuvant breast cancer therapy?

Impact of Metabolizing Enzymes on Drug Response of Endocrine Therapy in Breast Cancer Pilar H Saladores; Jana C Precht; Werner Schroth; Hiltrud Brauch; Matthias Schwab Disclosures ...

Inflammation is closely linked to the development and progression of cancer, as well as the effectiveness of cancer treatment. Inflammation is an immune response triggered when the immune system ...

The Seegar Lab used advanced cryogenic electron microscopy techniques to visualize the structure of the ADAM17 enzyme bound to its regulator protein, iRhom2, and identify key elements vital for ...

Understanding how drug delivery systems distribute in vivo remains a major challenge in developing nanomedicines. Especially in the lung, the complex and dynamic microenvironment often limits the ...