gut.bmj1d
Tumour-educated circulating monocytes are powerful candidate biomarkers for diagnosis and disease follow-up of colorectal cancer
Objective Cancer immunology is a growing field of research whose aim is to develop innovative therapies and diagnostic tests. Starting from the hypothesis that immune cells promptly respond to harmful ...
gut.bmj1d
Faecal metabolome and its determinants in inflammatory bowel disease
Objective Inflammatory bowel disease (IBD) is a multifactorial immune-mediated inflammatory disease of the intestine, comprising Crohn’s disease and ulcerative colitis. By characterising metabolites ...
gut.bmj2d
Epigenetic mechanisms and metabolic reprogramming in fibrogenesis: dual targeting of G9a and DNMT1 for the inhibition of liver fibrosis
Objective Hepatic stellate cells (HSC) transdifferentiation into myofibroblasts is central to fibrogenesis. Epigenetic mechanisms, including histone and DNA methylation, play a key role in this ...
gut.bmj2d
Role of mast cells in chronic stress induced colonic epithelial barrier dysfunction in the rat
Intestinal Disease Research Program, Department of Pathology and Molecular Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, L8N 3Z5, Canada M H Perdue, Intestinal Disease ...
gut.bmj2d
IDDF2020-ABS-0139 Global burden of gallbladder cancer and its associations with HDI, GDP, smoking, alcohol drinking, and overweight
1 Jockey Club School of Public Health and Primary Care, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong 2 Department of Gastroenterology, Ruijing Hospital North, School of Medicine, ...
gut.bmj4d
Irritable bowel syndrome: treatment based on pathophysiology and biomarkers
Objective To appraise the evidence that pathophysiological mechanisms and individualised treatment directed at those mechanisms provide an alternative approach to the treatment of patients with ...
gut.bmj4d
Microbiota-induced S100A11-RAGE axis underlies immune evasion in right-sided colon adenomas and is a therapeutic target to boost anti-PD1 efficacy
2 Key Laboratory of Human Microbiome and Chronic Diseases (Sun Yat-sen University), Ministry of Education, Guangzhou, China Background Tumourigenesis in right-sided and left-sided colons demonstrated ...
gut.bmj4d
Effect of endoscopic sleeve gastroplasty on gastric emptying, motility and hormones: a comparative prospective study
Correspondence to Dr Barham K Abu Dayyeh, Clinical Enteric Neuroscience Translational and Epidemiological Research (C.E.N.T.E.R), Division of Gastroenterology and Hepatology, Mayo Clinic Rochester, ...
gut.bmj5d
Fatigue in primary biliary cirrhosis
Mrs K Cauch-Dudek, Toronto Hospital, Western Division, 399 Bathurst St, West Wing 4–833, Toronto, Ontario M5T 2S8, Canada. Background—Fatigue is a frequent and debilitating symptom in patients with ...
gut.bmj5d
Proton pump inhibitors and risk of colorectal cancer
Objective To determine whether proton pump inhibitors (PPIs) are associated with an increased risk of colorectal cancer, compared with histamine-2 receptor antagonists (H2RAs). Design The United ...
gut.bmj6d
Mitogen activated protein (MAP) kinase signal transduction pathways and novel anti-inflammatory targets
1 Department of Gastroenterology and Hepatology, Academic Medical Centre, Amsterdam, the Netherlands 2 Department of Experimental Internal Medicine, Academic Medical Centre, Amsterdam, the Netherlands ...
gut.bmj6d
Effect of faecal occult blood screening on mortality from colorectal cancer: results from a randomised controlled trial
Background: Three large randomised trials have shown that screening for colorectal cancer using faecal occult blood (FOB) tests can reduce the mortality from this disease. Two national pilot studies ...