Adenosine deaminase 2 (ADA2) plays a critical role in immune regulation, particularly in monocyte differentiation and ...

By shutting this “off switch,” immune cells called macrophages regain their ability to soak up cholesterol, potentially ...

Researchers at UT Arlington have discovered a key enzyme, IDO1, that when blocked, helps immune cells regain their ability to ...

Scientists at The University of Texas at Arlington have identified a new enzyme that can be "turned off" to help the body ...

Scientists at The University of Texas at Arlington have identified a new enzyme that can be "turned off" to help the body ...

How do drug metabolizing enzymes such as CYP2D6 influence pharmacokinetics and drug efficiency of tamoxifen and aromatase inhibitors in adjuvant breast cancer therapy?

The evidence of CYP2D6 genotype–phenotype correlation associated with tamoxifen pharmacokinetics in early breast cancer is compelling. However, the scientific community is currently divided on ...

Inflammation is closely linked to the development and progression of cancer, as well as the effectiveness of cancer treatment. Inflammation is an immune response triggered when the immune system ...

The Seegar Lab used advanced cryogenic electron microscopy techniques to visualize the structure of the ADAM17 enzyme bound to its regulator protein, iRhom2, and identify key elements vital for ...

Nanogrid drug delivery systems developed for precise lung inflammation treatment by Liu Jia, Chinese Academy of Sciences edited by Gaby Clark, reviewed by Robert Egan Editors' notes ...

Johnson & Johnson Innovative Medicine has announced that the European Commission (EC) has approved a Marketing Authorisation (MA) for two new indications of TREMFYA ® (guselkumab), for the treatment ...