Ossification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone formation in the spine, leading to severe neurological symptoms due to spinal ...
News Medical on MSN19d
Single-cell transcriptome profiling identifies the activation of type I interferon signaling in ossified posterior longitudinal ligamentOssification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone formation in the spine, leading to severe neurological symptoms due to spinal ...
Interferon regulatory factor 3 (IRF3) is a key transcription factor in the type I interferon signaling. Its activation must be tightly controlled to efficiently activate innate immunity while avoiding ...
Type-1 interferons regulate immune responses and the production of self-reactive antibodies that target red blood cells in a SCD mouse model.
A new study in the peer-reviewed Journal of Interferon & Cytokine Research (JICR) showed that a specific retinoic ...
For example, activated T helper type 1 lymphocytes secrete interferon ... The authors suggest that inhibition of IFN-γ signaling could provide a novel approach for the concomitant prevention ...
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