The introduction of ATRA had prompted several study groups to explore the role of ATRA either as a single agent or in combination with chemotherapy. Although treatment with single-agent ATRA ...
How did you improve the administration of leukaemia treatment? The use of all-trans retinoic acid (ATRA) plus chemotherapy has been the standard therapy for APL, and has improved cure rates to ...
Although treatment of newly diagnosed APL with anthracycline-based chemotherapy combined with ATRA has been shown to be highly effective, limiting exposure to cytotoxic chemotherapy and ...