This was immediately followed by a 5-1 stretch in which the Cardinals got to 6-4 and first place in the NFC West. At this ...

500 finish and more meaningless games to play out the string on a fruitless season. But these Cardinals produced one final dominant win, beating the 49ers, 47-24, to finish 8-9. It was their largest ...

Preview the Week 18 matchup between the Arizona Cardinals and San Francisco 49ers with predictions, odds, over/under, spread, betting lines and more.

They suffered a blowout loss to the Arizona Cardinals, which is a fitting end to their year. So, without further introduction, here is the final four takeaways from the 49ers 47-24 loss to the ...

WR Jauan Jennings speaks out on his ejection against the Cardinals, calling it a mistake. Get the full details on his perspective.

Here are our experts' predictions for this NFC West matchup. The Cardinals are favorites to defeat the 49ers, according to the BetMGM NFL odds. Not interested in this game? Check out expert picks ...

What's the San Francisco 49ers vs Arizona Cardinals score? Follow our live updates for latest news, highlights, analysis from NFL Week 18 game.

Kyler Murray has started all 16 games for the Cardinals in his first full season back following knee surgery a couple seasons ago. The veteran has led the Cardinals through an up and down campaign ...

Last week against the Lions, the 49ers finished 100 percent, going five for five in the red zone. If the 49ers offense can produce this way against the Cardinals, the team will improve to 7-10. Tackle ...

With their talismanic QB out for their Week 18 clash with the Cardinals, the 49ers will sit Brock Purdy for their closer as they look ahead to next season.

GLENDALE, Ariz. -- Neither the Arizona Cardinals or San Francisco 49ers will be headed to the playoffs this season, but when rivals collide, like these two will at 4:25 p.m. Eastern Sunday on FOX ...

The Arizona Cardinals host the San Francisco 49ers on Sunday at 4:25 p.m. ET, in a battle featuring two outstanding receivers in Trey McBride and George Kittle. The Cardinals were defeated by the ...