Preview the Week 18 matchup between the Arizona Cardinals and San Francisco 49ers with predictions, odds, over/under, spread, betting lines and more.

They suffered a blowout loss to the Arizona Cardinals, which is a fitting end to their year. So, without further introduction, here is the final four takeaways from the 49ers 47-24 loss to the ...

WR Jauan Jennings speaks out on his ejection against the Cardinals, calling it a mistake. Get the full details on his perspective.

What's the San Francisco 49ers vs Arizona Cardinals score? Follow our live updates for latest news, highlights, analysis from NFL Week 18 game.

It was four months ago on Sept. 22 that the Arizona Cardinals lost in Week 3 to the Detroit Lions, 20-13. The Cardinals were ...

Jess Root and Seth Cox talk about the final win and the totality of the 2024 season in the latest show for the podcast.

D.J. Reed's path to free agency started with the San Francisco 49ers, who drafted him in the fifth round of the 2018 NFL ...

With their talismanic QB out for their Week 18 clash with the Cardinals, the 49ers will sit Brock Purdy for their closer as they look ahead to next season.

Last week against the Lions, the 49ers finished 100 percent, going five for five in the red zone. If the 49ers offense can produce this way against the Cardinals, the team will improve to 7-10. Tackle ...

The Arizona Cardinals host the San Francisco 49ers on Sunday at 4:25 p.m. ET, in a battle featuring two outstanding receivers in Trey McBride and George Kittle. The Cardinals were defeated by the ...

The San Francisco 49ers (6-10) and Arizona Cardinals (7-9) will look to wrap up their seasons on a high note when the meet Sunday in a Week 18 battle of teams that have been eliminated from the ...

GLENDALE, Ariz. -- Neither the Arizona Cardinals or San Francisco 49ers will be headed to the playoffs this season, but when rivals collide, like these two will at 4:25 p.m. Eastern Sunday on FOX ...